This is a matter of personal preference. If this is a concern, Plantronics would recommend requesting a trial from the supplier to be sure the headset does suit the individual.
Plantronics headsets only come in 2 styles: headband or earloop.
· Headbands are ideal as the vertical weight is nowhere near the glasses and hence the ear cushions rest against your ear(s) and do not interfere with the legs of glasses
· Earloops can come with 2 wearing styles regarding glasses. For the CS60 and the DuoSet (H141), the end of the glasses 'leg' can sit in the grove over the earloop. All ear loops can also rest beside as well.